A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer’s-associated protein amyloid beta in the brain is tightly regulated by cholesterol. Appearing online Thursday ahead of print in the Aug. 17 issue of the Proceedings of the National Academy of Sciences, the scientists’ work advances understanding of how Alzheimer’s disease develops and underscores the long-underappreciated role of brain cholesterol. A co-senior author of the study was Dr. Heather Ferris, assistant professor in the Department of Medicine at the UVA Scho...