Researchers from the University of Virginia in Charlottesville were interested in identifying independent risk factors associated with inappropriate, empiric antimicrobial therapy for the treatment of severe sepsis. Their retrospective analysis of a prospectively maintained database of all surgical/trauma patients admitted to a tertiary care center appears in the July 2014 issue of the Journal of Trauma and Acute Care Surgery. The investigators analyzed data from 1996 to 2007, looking patients who developed postsurgical sepsis and they identified 2,855 patients who experienced 7,158 infections...