People with Parkinson’s disease with symptoms affecting one side of the body, who were treated with focused ultrasound targeting the affected brain region, showed an improvement in motor features after four months, a small study reported. To clarify the procedure’s effectiveness and safety, researchers at the University of Virginia, in collaboration with Spain’s Centro Intregral de Neurociencias, conducted a randomized, sham-controlled trial of focused ultrasound in a group of patients with highly asymmetric motor signs not fully controlled by medication.