The Tuskegee Study, in which doctors purposefully neglected to provide appropriate treatment to Black men in order to study the long-term effects of syphilis, lasted from 1932 to 1972 and gave Black Americans ample cause to distrust medical researchers. “To this day it is likely why a large portion of our unrepresented minorities are going to have a fear of wanting to enroll in trials,” says Siddhartha S. Angadi, a UVA cardiovascular-exercise physiologist.