What Is Biotechnology? Where Is It Headed at UVA?

January 20, 2023 By Eric Williamson, williamson@virginia.edu Eric Williamson, williamson@virginia.edu

With the announcement of the Paul and Diane Manning Institute of Biotechnology at the University of Virginia, you may be asking yourself: “What exactly is biotechnology?”

If so, you’re not alone. The term is familiar, yet it has been so broadly invoked as to be unclear to many people.

In medicine, one might think of the latest gene therapies, for example. But biotechnology has been associated with breakthroughs in everything from agriculture (biofuels and genetically modified crops) to consumer products (detergent enzymes and skin care).

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UVA Today spoke to Dr. Richard Price, a biomedical engineer who co-directs the UVA Focused Ultrasound Cancer Immunotherapy Center, about the definition of biotechnology and the role it plays at UVA Health.

Portrait of Dr. Richard Price

Dr. Richard Price is the Lawrence R. Quarles Professor of Biomedical Engineering. He co-directs the UVA Focused Ultrasound Cancer Immunotherapy Center and is a professor of radiology and medical imaging. (UVA Health photo)

What Is Biotechnology?

Price said context helps when discussing what biotechnology means.

“To me, the term ‘biotechnology’ has conventionally meant the process of modifying organisms, typically cells in culture or bacteria, to be machines that create a beneficial product,” he said. “These are often substances and drugs that are used in health care.”

But he said the field can, and arguably should, be viewed more broadly.

“At UVA, while important research under my more conventional take on biotechnology is robust and important, I think we also include a broader perspective,” he said. “To me at least, biotechnology at this institution also encompasses engineering new technologies and devices, not necessarily organisms, that improve human health. Such research has an eye toward helping patients right from the start.”

UVA’s chemists and medical researchers have been working for decades in the biotech space. The University, as a result, has a renowned Biotechnology Training Program for graduate students – one of only 19 such programs in the nation.

For the purposes of the Paul and Diane Manning Institute of Biotechnology, the focus will be specifically on translational medicine – the highly collaborative “bench-to-bedside” approach that speeds innovations from laboratory benches to the real patients who need them.

What Is the Future of Biotech at UVA?

Through the institute, UVA will continue to build on its expertise in medical biotechnology. The effort will benefit in particular from UVA’s newly enhanced ability to manufacture gene and cell therapy solutions at a large scale to support clinical trials and other essential steps in the development process toward FDA approval.

To get a sense of what the future holds, it’s worth looking to the recent past. Here are a few of UVA Health’s latest breakthroughs.

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UVA Health