The sexual side-effect rates from the current survey are lower than those we found in 2004, when up to 53 percent of respondents reported them. "It's possible that health-care providers are either prescribing antidepressants that are less likely to cause these problems, such as bupropion (Wellbutrin and generic) or are adding another drug in as an antidote to help counteract the sexual side effects," said Anita Clayton, M.D., a professor of psychiatry and obstetrics and gynecology at the University of Virginia.